脓毒症心肌损伤发病机制及治疗研究进展

doi:10.3969/j.issn.1006⁃5725.2023.14.021

Abstract

Abstract:

Sepsis is an organ dysfunction caused by the host′s uncontrolled response to infection，and is a common cause of death in critically ill patients. Sepsis ⁃induced myocardial injury（SIMI）directly related to the poor prognosis of sepsis. The pathogenesis of SIMI is complex and related to mechanisms such as excessive inflam⁃ matory response，mitochondrial damage，cell apoptosis，and autophagy. Deeply exploring the pathogenic mecha⁃ nism of SIMI can help develop more effective targeted drugs，thereby improving the prognosis of sepsis patients.

Key words: sepsis, cardiomyopathy, pathogenesis, treatment

HUANG Ying, TANG Lili, GUAN Yulin, ZHANG Jie, LI Xiaoyue.. Research progress on the pathogenesis and treatment of sepsis⁃induced myocardial injury [J]. The Journal of Practical Medicine, 2023, 39(14): 1848-1852.

[1]	Yuan LI,Huiling LIU,Dan WU,Baobao. LI. Research advances of virulence factors in recurrent vulvovaginal candidiasis [J]. The Journal of Practical Medicine, 2024, 40(16): 2347-2351.
[2]	GUO Haiwen, YU Shaowei.. Research progress in diagnosis of specific learning disorder [J]. The Journal of Practical Medicine, 2023, 39(4): 395-399.
[3]	Xue AO,Xing SU,Yu HOU,Tianyi MA,Chao. DENG. P38MAPK/NF⁃κB⁃based study of the molecular mechanism of miR⁃146a intervention in septic cardiomyopathy [J]. The Journal of Practical Medicine, 2023, 39(24): 3188-3194.
[4]	Jianfeng ZHANG,Bin YU,Zhenya ZHANG,Guiying. WANG. Advances in the diagnosis and treatment of postoperative delirium in colorectal cancer [J]. The Journal of Practical Medicine, 2023, 39(20): 2687-2690.
[5]	LI Junjie, FENG Yan, SUN Defeng.. Progress in the clinical application of the analgesic effect of S⁃ketamine [J]. The Journal of Practical Medicine, 2023, 39(2): 180-185.
[6]	DAI Ziyi, WU Weidong, LI⁃ANG Jifang, YAN Xinming.. Research progress of short chain fatty acids balance in the treatment of sepsis [J]. The Journal of Practical Medicine, 2022, 38(3): 266-270.
[7]	MA Ying, HUANG Sixia, HUANG Liujing, CAI Zhaoxia, MA Song, LIANG Xiaoshan.. Microbiomics：A new direction in etiology of endometriosis [J]. The Journal of Practical Medicine, 2022, 38(24): 3027-3031.
[8]	CAO Lijun, HUANG Yingwen, HE Xueqiang, MO Chunrong, XIONG Hong, ZHOU Xianbao, LU Shuihuan, WANG Lin, LUO Yanying, JIANG Shifang.. Efficacy and safety of emergency endoscopic retrograde cholangiopancreatography in super elderly patients with acute obstructive suppurative cholangitis [J]. The Journal of Practical Medicine, 2022, 38(23): 2957-2961.
[9]	LI Yunting, LI Fen, XING Bo.. Analysis of risk factors of concurrent ICU acquired weakness in elderly patients with sepsis undergoing me⁃ chanical ventilation and the early predictive value of mNUTRIC score [J]. The Journal of Practical Medicine, 2022, 38(20): 2568-2573.
[10]	ZHONG Rongbin, RAO Ming⁃ cong , HUANG Minfang.. Research progress in comorbidity of obstructive sleep apnea with insomnia [J]. The Journal of Practical Medicine, 2022, 38(2): 134-138.
[11]	ZHANG Jingwen, CAO Xinguang, FU Yang, JIAO Wenyun, LIU Liang, GUO Changqing.. Comparison of therapeutic effects between endoscopic and surgical treatment of 2 ~ 5 cm gastric stromal tumor [J]. The Journal of Practical Medicine, 2022, 38(19): 2451-2456.
[12]	LI Ying, LI Qing, WANG Xuan, ZHOU Lijun, TAN Zhi. . Research advances in burning mouth syndrome [J]. The Journal of Practical Medicine, 2022, 38(19): 2486-2490.
[13]	LI Li, ZHOU Jiahe, LI Mojuan, ZHONG Minglin, ZHANG Xiaowei, XU Qiuyi, LIANG Li⁃ anyun.. A frontier review and an outlook on epigenetics，metabolomics，and gut microbiota mechanism of polycystic ovary syndrome [J]. The Journal of Practical Medicine, 2022, 38(16): 1987-1992.
[14]	GAO Ke⁃ fei, ZENG Gen, YUAN Shuo, LU Ruling, LI Sijin, DU Miaomiao, ZHAO Eryong, YI Lisha, LIU Yaqiong, CHEN Weiwei, HE Xiaoqian, QIU Jiahan, BU Yali , YANG Chuanzi.. A comparative study of Traditional Chinese and Western medicine on the maintenance treatment of stage Ⅲ ovarian endometriomas with Luo′s Endometriosis Formula and combined oral contraceptives [J]. The Journal of Practical Medicine, 2022, 38(16): 2086-2093.
[15]	ZOU Suwen, ZHU Caixia, ZHANG Anqin. Glucocorticoid management of granulomatous mastitis：A review of literature [J]. The Journal of Practical Medicine, 2022, 38(13): 1711-1714.

Research progress on the pathogenesis and treatment of sepsis⁃induced myocardial injury

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments